10
sites offering dedicated flow cytometry expertise
25+
years of experience
~50
flow cytometers globally
130+
scientific and technical staff dedicated to flow cytometry
Unlock Deeper Insights with Expert Flow Cytometry Services
We deliver high-quality, high-throughput flow cytometry services tailored to accelerate your research, from discovery through clinical development.
Whether you’re conducting immunophenotyping, receptor occupancy, cell sorting, biomarker analysis or functional assays, our state-of-the-art platforms (conventional or spectral) and experienced team of scientists ensure optimal panel design and sample analysis with precision, reproducibility, and fast turnaround times.
Flow Cytometry That Validates, Innovates, and Delivers
Flow cytometry has the power to transform drug development when it’s done with precision, foresight, and purpose. Programs often face the same hurdles – incomplete assay validation, outdated instrumentation, fragmented workflows, and a lack of regulatory alignment, resulting in delays, uncertainty, and missed opportunities.
Our service integrates rigorous assay development and validation, aligned with GLP/GCP compliance, to ensure that every data point stands up to scientific and regulatory scrutiny. By staying ahead of flow cytometry trends, we help sponsors adapt to emerging capabilities, from high-dimensional immune profiling to novel probe development.
Through Retrogenix® HIT validation, we pinpoint off-target interactions early, de-risking candidate selection and strengthening downstream success. With custom assay development and comprehensive cell profiling, we deliver the flexibility and depth needed to answer your study’s most critical questions.
This isn’t just flow cytometry as a service; it’s a strategic partner in your biomarker journey, designed to validate today’s work and anticipate tomorrow’s breakthroughs.
Flow Cytometry Assays in Clinical Trials
Flow cytometry is a powerful tool that has been increasingly used in clinical trials to assess immunotherapy candidates. Cell-based modalities such as CAR-T and CAR-NK cell therapies often utilize flow cytometry to monitor the persistence and differentiation of the cell therapy products and their pharmacology by monitoring target cell depletion.
Flow Cytometry Trends
Our Scientific Director for immunology, Marie-Soleil Piche, discusses the latest trends in flow cytometry.
Immunophenotyping
Immunophenotyping is an important endpoint to evaluate the impact of a pharmaceutical compound on the immune system. Selecting the correct markers for inclusion within an immunophenotyping assessment should consider the mode of action and how it will modify cell populations. Our experienced teams can help you design the most appropriate panel of markers to make more accurate assessments.
Retrogenix® Hit Validation via Flow Cytometry
Further analyze your hits using flow cytometry. This add-on service can be applied to hit validation via Retrogenix® Microarray Technology. Retrogenix hit validation via flow cytometry services routinely follows on from a full screen, often using materials available at the end of the main screen avoiding the need to produce and ship further samples.
Unlock the Full Potential of Biomarkers
Discover how to connect biomarker insights from early discovery to clinical trials to accelerate timelines, reduce risk, and improve decision-making. Our expert guide shows you how to integrate the right strategies and technologies to deliver impactful data.
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Advanced Flow Cytometry that Drives Deeper Insights
Our flow cytometry services combine cutting-edge technology with expert assay design to provide high-resolution cellular analysis across a wide range of applications. Each capability is built to generate reproducible, GLP-/GCP-compliant data that informs critical development decisions.
Immunophenotyping and Comprehensive Cell Profiling
Multi-maker immune cell identification and population analysis across diverse sample types to characterize immune responses and detect rare cell subsets.
Cell Signaling and Pathway Analysis
Quantify intercellular signaling events to reveal pathway activation or inhibition, supporting mech intracellular signaling events to reveal pathway activation or inhibition, supporting mechanism-of-action studies and therapeutic targeting.
Cell Cycle and Proliferation
Determine cell cycle phases and monitor proliferation rates to evaluate compound effects on cellular growth and division.
Apoptosis and Viability Testing
Assess programmed cell death and overall viability using multi-parameter staining to support safety and efficacy evaluations.
Antigen, Receptor, and Ligand Density and Occupancy
Measure surface or intracellular molecule expression and drug-target binding efficiency for precise pharmacodynamic assessments.
Functional Tumor Killing and Phagocytosis Assays
Evaluate immune cell-mediated tumor killing and phagocytic activity in real time to confirm functional immune responses.
Enzyme Activity and Intracellular Storage Studies
Detect and quantify enzymatic function and intracellular compound storage to understand metabolic processes and therapeutic impact.
eGuide: Biomarker Solutions from Discovery to Clinical Trials
Learn how strategic biomarker integration can accelerate research and de-risk pipelines to bring life-saving therapies to patients faster. This guide helps you uncover smarter ways to de-risk studies and accelerate timelines, without compromising scientific rigor.
Read the Guide
Global Flow Cytometry Excellence with Regulatory Rigor
Flow cytometry is only as powerful as the technology, expertise, and infrastructure behind it. Studies are often slowed down or compromised by outdated instruments, generic assay approaches, or inconsistent results across sites.
Our approach eliminates those limitations. By combining cutting-edge platforms with custom assay development and comprehensive cell profiling, we deliver richer, more relevant data tailored to your study’s objectives. Our global footprint ensures harmonized processes and consistent quality anywhere in the world, while GLP/GCP compliance safeguards your results for regulatory submission.
This is flow cytometry built to answer your most critical questions, faster, more accurately, and with the confidence that every data point is ready for decision-making.
Cutting-edge technology
We utilise advanced conventional and spectral flow cytometers (up to 50+ flow cytometers globally) with capabilities for analysis of any sized panel.
Custom assay development
Our team works closely with you to design, validate, and optimize assays that align with your specific goals-no matter how complex the study.
Comprehensive cell profiling
From T-cell subsets and activation markers to rare population detection, we provide detail immune phenotyping for early discovery to clinical sample analysis support.
Global footprint
Due to our global footprint, we can transfer and validate flow cytometry assays to our sites around the world. Additional infrastructure allows us to accommodate the receipt of samples 24/7/365 to support their timely analysis with limited stability.
GCLP
Although it is not a requirement for all clinical flow cytometry assessments, we are capable of performing work in compliance with Good Clinical Laboratory Practice (GCLP). Additionally, individual sites may configure clinical assays for CLIA compliance where appropriate.
The Scope of Flow Cytometry Applications
Flow cytometry is one of the most versatile tools in modern drug development, capable of delivering deep cellular insights across a spectrum of scientific and clinical needs. From foundational immune cell profiling to advanced functional assays, its applications span discovery through late-stage trials.
The visuals below outline core and advanced applications supported by our platforms, including immunophenotyping, signaling pathway analysis, viability testing, antigen/receptor quantifications, tumor-killing, phagocytosis, enzyme activity and more. By integrating these capabilities withing a harmonized, GLP/GCP-compliant framework, we provide the technical expertise and precision needed to answer your most critical questions.
Frequently Asked Questions (FAQs) for Flow Cytometry Services
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What stages of the drug development pipeline do your flow cytometry services support?
Clients often need reassurance that a provider can support everything from early discovery through clinical trials. Highlighting your preclinical and clinical capabilities, including custom assay development and GLP/GCP-compliant workflows, can set you apart.
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How do you ensure scientific rigor and regulatory compliance in your assays?
Buyers look for validated, reliable results. Emphasizing your quality control processes, regulatory-aligned validation, and data integrity demonstrates readiness for submissions and minimizes development risk.
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Can you customize assays and panels to fit specific molecules or therapeutic targets?
Flexibility matters, especially when dealing with novel targets or complex modalities. Showcasing your custom assay development, panel design expertise, and ability to replicate published protocols speaks to your scientific agility.
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What throughput and instrument capabilities do you offer?
Technical specifications matter. From the number of fluorescent channels to total throughput. Clients often compare instrumentation stats, such as high-parameter spectral systems or high-throughput automation platforms, when choosing a provider.